Super Conserved Receptor Expressed in Brain explained

G protein-coupled receptor 27
Hgncid:4482
Symbol:GPR27
Altsymbols:SREB1
Entrezgene:2850
Omim:605187
Refseq:NM_018971
Uniprot:Q9NS67
Chromosome:3
Arm:p
Band:21
Locussupplementarydata:-p14
G protein-coupled receptor 85
Hgncid:4536
Symbol:GPR85
Altsymbols:SREB2
Entrezgene:54329
Omim:605188
Refseq:NM_018970
Uniprot:P60893
Chromosome:7
Arm:q
Band:31
G protein-coupled receptor 173
Hgncid:18186
Symbol:GPR173
Altsymbols:SREB3
Entrezgene:54328
Omim:300253
Refseq:NM_018969
Uniprot:Q9NS66
Chromosome:X
Arm:p
Band:11

The Super Conserved Receptor Expressed in Brain (SREB) family are a group of related G-protein coupled receptors.[1] Since no endogenous ligands have yet been identified for these receptors, they are classified as orphan receptors. Receptors within the group include SREB1 (GPR27), SREB2 (GPR85), and SREB3 (GPR173).[2]

External links

Notes and References

  1. Matsumoto M, Saito T, Takasaki J, Kamohara M, Sugimoto T, Kobayashi M, Tadokoro M, Matsumoto S, Ohishi T, Furuichi K . An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system . Biochem. Biophys. Res. Commun. . 272 . 2 . 576–82 . 2000 . 10833454 . 10.1006/bbrc.2000.2829 .
  2. National Center for Biotechnology Information, Conserved Protein Domain Family7tmA_SREB1_GPR27, accessed 5 February 2022