Sunghoon Kwon Explained

Sunghoon Kwon
Field:Medical Engineering, Bioengineering, Electrical Engineering and Computer Science
Prizes:2011 Young Scientist Award
2012 SNU Creative Leading Researcher
2013 The Jin-gi Hong Creativity Award
2013 The 4th annual Yumin Awards
2014 Lectureship Award on Chemical Society of Japan
2016 IT Young Engineer Award
2018 Young Engineer Award
2018 The 13th Pioneers of Miniaturization Lectureship
2019 Jin-Pok Kim's Award for the Best Cancer Research in Korea
2019 National R & D Performance Evaluation Merit Award
Known For:BioMEMS, Lab on a Chip, Single cell sequencing, Immune Profiling
Doctoral Advisor:Luke Pyungse Lee
Alma Mater:University of California, Berkeley
Workplaces:Seoul National University
Nationality:Korea, Republic of
Birth Date:December 23, 1975

Sunghoon Kwon (born 23 December 1975) a biomedical engineer and an entrepreneur. He is the professor of Electrical and Computer Engineering at Seoul National University in Republic of Korea and the CEO of Quantamatrix.

Education and early life

Sunghoon Kwon was born on 23 December 1975 in Seoul; he studied at Yeoksam Middle School and Sangmun High School; he studied at the Department of Electrical Engineering at Seoul National University to become a programmer because he was interested in computer programming since he was a child. In the third year of college, he was admitted to the hospital due to a serious traffic accident, and his dream changed to biomedical engineering as he saw electronic and electrical technologies such as Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) play an important role in medicine.Sunghoon Kwon studied medical devices mainly for doctors at the Department of Medical Engineering at Seoul National University and received a master's degree with the theme of developing a wireless mouse that moves according to eye movements for the disabled. Later, he entered the doctoral program at UC Berkeley, where he studied bio / optical MEMS and lab on a chip system for biomaterial analysis. In 2003, he completed his Ph.D. under the supervision of Luke Pyungse Lee.[1] in three and a half years and studied nanomaterials and nanoprocessing at the Lawrence Berkeley National Laboratory.

Career

Ever since he was appointed professor of the Department of Electrical and Computer Engineering at Seoul National University, he always wanted to give tools or devices to life scientists and medical doctors that they needed in their cutting edges, to enable innovations. Therefore, for the last 14 years, he and his group have worked towards realization of personalized medicine under the motto: “helping life scientist with technology.” and have made technological breakthroughs in personalized medicine that resulted in 80 scientific literatures, 130 patents and 2 spun-off companies hiring more than 200 full-time employees. He focused on developing technologies for life scientists and medical doctors to improve personalized therapeutics to reduce the breakdown cost for disease treatment.

Kwon's research includes work on multiplex bio assay platform,[2] [3] [4] [5] [6] [7] single cell analysis[8] [9] [10] [11] [12] [13] and algorithm for immune profiling[14]

Awards and honors

Sunghoon Kwon was invited to deliver a Plenary Talk in IEEE OMN (2020) and delivered invited lectures in prominent international conferences including TEDx talk in Korea Foundation for Advanced Studies (KFAS) (2018), Plenary Talk in IEEE MEMS (the first Korean Plenary Talk in 31 years history of IEEE MEMS conference) (2017) and more plenary talks and invited talks.

He was appointed as one of the eight SNU Creative Distinguished Professors (Similar to University Professorship, $660k) of the Seoul National University in 2012. He gained academic recognition of his excellence from both engineering and science by winning many awards including the Young Scientist Award, The Korea Academy of Science and Technology (2011), Korean Young Scientist Award ($100k) from the Korean President, presidential award given to 4 scientists under age of 40 (2012), IEEK/IEEE Joint Awards IT Young Engineer Award (2016), Young Engineer Award ($44k) from the National Academy of Engineering of Korea (2018) and Jin-Pok Kim's Award for the Best Cancer Research in Korea from Korea Cancer Research Foundation (2019). Kwon is one of few scientists who has early career awards from both National Science Academy and National Engineering Academy at the same time. He is the first Korean winner of the 13th Pioneers of Miniaturization Lectureship, Lab on a Chip Journal (2018).

Kwon is a member of NAEK, the National Academy of Engineering of Korea (2020) that appoints engineers who make remarkable contributions to the technological development, and a member of Y-KAST, young Korean Academy of Science and Technology (2017) that is given to innovative scientists under 45. Kwon served in many technical program committees in prominent societies, like MicroTAS, IEEE MEMS, and Transducers.

Selected publications

  1. Lim, D. K.; Jeon, K. S.; Hwang, J. H.; Kim, H.; Kwon, S.; Suh, Y. D.; & Nam, J. M. (2011). Highly uniform and reproducible surface-enhanced Raman scattering from DNA-tailorable nanoparticles with 1-nm interior gap. Nature nanotechnology, 6(7), 452. doi:https://doi.org/10.1038/nnano.2011.79
  2. Kim, H.; Ge, J.; Kim, J.; Choi, S. E.; Lee, H.; Lee, H.; Park, W.; Yin, Y.; & Kwon, S. (2009). Structural colour printing using a magnetically tunable and lithographically fixable photonic crystal. Nature Photonics, 3(9), 534–540. doi:https://doi.org/10.1038/nphoton.2009.141
  3. Chung, S. E.; Park, W.; Shin, S.; Lee, S. A.; & Kwon, S. (2008). Guided and fluidic self-assembly of microstructures using railed microfluidic channels. Nature materials, 7(7), 581–587. doi:https://doi.org/10.1038/nmat2208
  4. Chan, S.; Kwon, S.; Koo, T. W.; Lee, L. P.; & Berlin, A. A. (2003). Surface‐Enhanced Raman Scattering of Small Molecules from Silver‐Coated Silicon Nanopores. Advanced Materials, 15(19), 1595–1598. doi:https://doi.org/10.1002/adma.200305149
  5. Lee, H.; Kim, J.; Kim, H.; Kim, J.; & Kwon, S. (2010). Colour-barcoded magnetic microparticles for multiplexed bioassays. Nature materials, 9(9), 745–749. doi:https://doi.org/10.1038/nmat2815
  6. Kim, J.; Chung, S. E.; Choi, S. E.; Lee, H.; Kim, J.; & Kwon, S. (2011). Programming magnetic anisotropy in polymeric microactuators. Nature materials, 10(10), 747-752. doi:https://doi.org/10.1038/nmat3090
  7. Ge, J.; Lee, H.; He, L.; Kim, J.; Lu, Z.; Kim, H.; Goebl, J.; Kwon, S.; & Yin, Y. (2009). Magnetochromatic microspheres: rotating photonic crystals. Journal of the American Chemical Society, 131(43), 15687–15694. doi:https://doi.org/10.1021/ja903626h
  8. Chung, S. E.; Park, W.; Park, H.; Yu, K.; Park, N.; & Kwon, S. (2007). Optofluidic maskless lithography system for real-time synthesis of photopolymerized microstructures in microfluidic channels. Applied Physics Letters, 91(4), 041106. doi:https://doi.org/10.1063/1.2759988
  9. Choi, J.; Yoo, J.; Lee, M.; Kim, E. G.; Lee, J. S.; Lee, S.; Joo, S.; Song, S. H.; Kim, E.; Lee, J. C.; Kim, H. C.; Jung, Y.; & Kwon, S. (2014). A rapid antimicrobial susceptibility test based on single-cell morphological analysis. Science translational medicine, 6(267), 267ra174-267ra174.
  10. Bae, H. J.; Bae, S.; Park, C.; Han, S.; Kim, J.; Kim, L. N.; Kim, K.; Song, S.; Park, W.; & Kwon, S. (2015). Biomimetic Microfingerprints for Anti‐Counterfeiting Strategies. Advanced Materials, 27(12), 2083–2089. doi:https://doi.org/10.1002/adma.201405483

External links

Notes and References

  1. KWON, Sunghoon; LEE, Luke P. Micromachined transmissive scanning confocal microscope. Optics letters, 2004, 29.7: 706-708.
  2. Kim. Hyoki. Ge. Jianping. Kim. Junhoi. Choi. Sung-eun. Lee. Hosuk. Lee. Howon. Park. Wook. Yin. Yadong. Kwon. Sunghoon. September 2009. Structural colour printing using a magnetically tunable and lithographically fixable photonic crystal. Nature Photonics. en. 3. 9. 534–540. 10.1038/nphoton.2009.141. 2009NaPho...3..534K . 1749-4885.
  3. Lee. Howon. Kim. Junhoi. Kim. Hyoki. Kim. Jiyun. Kwon. Sunghoon. September 2010. Colour-barcoded magnetic microparticles for multiplexed bioassays. Nature Materials. en. 9. 9. 745–749. 10.1038/nmat2815. 20729849. 2010NatMa...9..745L . 1476-1122.
  4. Han. Sangkwon. Bae. Hyung Jong. Kim. Junhoi. Shin. Sunghwan. Choi. Sung-Eun. Lee. Sung Hoon. Kwon. Sunghoon. Park. Wook. 2012-11-20. Lithographically Encoded Polymer Microtaggant Using High-Capacity and Error-Correctable QR Code for Anti-Counterfeiting of Drugs. Advanced Materials. en. 24. 44. 5924–5929. 10.1002/adma.201201486. 22930454. 2012AdM....24.5924H . 5100421 .
  5. Eun Chung. Su. Kim. Jiyun. Yoon Oh. Dong. Song. Younghoon. Hoon Lee. Sung. Min. Seungki. Kwon. Sunghoon. May 2014. One-step pipetting and assembly of encoded chemical-laden microparticles for high-throughput multiplexed bioassays. Nature Communications. en. 5. 1. 3468. 10.1038/ncomms4468. 24632848. 2014NatCo...5.3468E . 2041-1723. free.
  6. Lee. Howon. Kim. Hyoki. Kim. Sungsik. Ryu. Taehoon. Kim. Hwangbeom. Bang. Duhee. Kwon. Sunghoon. May 2015. A high-throughput optomechanical retrieval method for sequence-verified clonal DNA from the NGS platform. Nature Communications. en. 6. 1. 6073. 10.1038/ncomms7073. 2041-1723. 4327316. 25641679. 2015NatCo...6.6073L .
  7. Choi. J.. Yoo. J.. Lee. M.. Kim. E.-G.. Lee. J. S.. Lee. S.. Joo. S.. Song. S. H.. Kim. E.-C.. Lee. J. C.. Kim. H. C.. 2014-12-17. A rapid antimicrobial susceptibility test based on single-cell morphological analysis. Science Translational Medicine. en. 6. 267. 267ra174. 10.1126/scitranslmed.3009650. 25520395. 22448314 . 1946-6234.
  8. Constructing and Visualizing Cancer Genomic Maps in 3D Spatial Context by Phenotype-based High-throughput Laser-aided Isolation and Sequencing (PHLI-seq). Kim. Sungsik. Lee. Amos Chungwon. 2018-03-07. Lee. Han-Byoel. Kim. Jinhyun. Jung. Yushin. Ryu. Han Suk. Lee. Yongju. Bae. Sangwook. Lee. Minju. 10.1101/278010. 89748404 .
  9. Evaluating Tumor Evolution via Genomic Profiling of Individual Tumor Spheroids in a Malignant Ascites from a Patient with Ovarian Cancer Using a Laser-aided Cell Isolation Technique. Kim. Sungsik. Kim. Soochi. 2018-03-15. Kim. Jinhyun. Kim. Boyun. Kim. Se Ik. Kim. Min A. Kwon. Sunghoon. Song. Yong Sang. 10.1101/282277. 91065482 .
  10. Kim. Namhee. Choi. Seongmin. Kim. Sung-Min. Lee. Amos Chungwon. Im. Kyongok. Park. Hee Sue. Kim. Jung-Ah. Kim. Kwangsoo. Kim. Inho. Chang. Yoon Hwan. Lee. Dong Soon. 2019-02-04. Monozygotic twins with shared de novo GATA2 mutation but dissimilar phenotypes due to differential promoter methylation. Leukemia & Lymphoma. 60. 4. 1053–1061. 10.1080/10428194.2018.1516039. 30714451. 73423322 . 1042-8194.
  11. Shin. Dong Woo. Kim. Sung-Min. Kim. Jung-Ah. Park. Hee Sue. Hwang. Sang Mee. Im. Kyongok. Kim. Sungsik. Kim. Jinhyun. Kwon. Sunghoon. Yoon. Sung-Soo. Lee. Dong Soon. August 2019. Characteristics of Waldenström Macroglobulinemia in Korean Patients According to Mutational Status of MYD88 and CXCR4: Analysis Using Ultra-Deep Sequencing. Clinical Lymphoma, Myeloma & Leukemia. 19. 8. e496–e505. 10.1016/j.clml.2019.03.009. 31221512. 2152-2650. free.
  12. Kim. Okju. Lee. Daewon. Chungwon Lee. Amos. Lee. Yongju. Bae. Hyung Jong. Lee. Han‐Byoel. Kim. Ryong Nam. Han. Wonshik. Kwon. Sunghoon. September 2019. Single Cell Genomics: Whole Genome Sequencing of Single Circulating Tumor Cells Isolated by Applying a Pulsed Laser to Cell‐Capturing Microstructures (Small 37/2019). Small. 15. 37. 1970196. 10.1002/smll.201970196. 1613-6810.
  13. Lee. Amos C.. Svedlund. Jessica. Darai. Evangelia. Lee. Yongju. Lee. Daewon. Lee. Han-Byoel. Kim. Sung-Min. Kim. Okju. Bae. Hyung Jong. Choi. Ahyoun. Lee. Sumin. 2020. OPENchip: an on-chip in situ molecular profiling platform for gene expression analysis and oncogenic mutation detection in single circulating tumour cells. Lab on a Chip. 20. 5. 912–922. 10.1039/c9lc01248f. 32057051. 211113095 . 1473-0197.
  14. Kim. Soohyun. Lee. Hyunho. Noh. Jinsung. Lee. Yonghee. Han. Haejun. Yoo. Duck Kyun. Kim. Hyori. Kwon. Sunghoon. Chung. Junho. 2019-01-18. Efficient Selection of Antibodies Reactive to Homologous Epitopes on Human and Mouse Hepatocyte Growth Factors by Next-Generation Sequencing-Based Analysis of the B Cell Repertoire. International Journal of Molecular Sciences. 20. 2. 417. 10.3390/ijms20020417 . 6359367 . 30669409. 1422-0067. free.

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