Sulforidazine Explained

Sulforidazine (Imagotan, Psychoson, Inofal) a typical antipsychotic and a metabolite of thioridazine; it and mesoridazine are more potent than the parent compound, whose pharmacological effects are believed by some to be largely due to its metabolism into sulforidazine and mesoridazine.^[1]

Synthesis

2-bromo-2'-amino-4'-methylsulphonyl-diphenyl Sulphide, CID:43448246 (1)2-bromo-2'-acetamino-4'-methylsulphonyl diphenylsulphide (2)2-(2-Chloroethyl)-1-Methylpiperidine [50846-01-0] (3)

Notes and References

1. Niedzwiecki DM, Mailman RB, Cubeddu LX . Greater potency of mesoridazine and sulforidazine compared with the parent compound, thioridazine, on striatal dopamine autoreceptors. Journal of Pharmacology and Experimental Therapeutics. March 1984 . 228 . 3. 636–9. 6707914.