Suloctidil Explained

Suloctidil was a sulfur-containing aminoalcohol that was brought to market in the early 1970s as a vasodilator by Continental Pharma, a Belgian company.[1] [2] [3]

Continental was bought by Monsanto in 1984, primarily on the promise of sales of suloctidil, which was approved in Europe at the time, but not in the US.[4] However, in 1985 Monsanto halted development and withdrew the drug worldwide following reports of liver toxicity.[5]

Notes and References

  1. Book: Hladovec, Josef . Antithrombotic Drugs in Thrombosis Models . CRC Press . 1989 . 978-0-8493-5162-4 .
  2. Roncucci R, Roba J, Lambelin G, Ferenczi M, Blaton V, Vandamme D, Peeters H . Potential antilipolytic activity of suloctidil . Die Naturwissenschaften . 62 . 3 . 141–2 . March 1975 . 1240601 . 10.1007/bf00623284 . 1975NW.....62..141R . 29484315 .
  3. BE . 739678 . granted . 1-Subst-phenyl-2-amino-ethanols useful as beta adrenergic agents peripheral vasodilators and hypotensive agents . Buu-Hoi NP, Lambelin G, Roba J, Jacques G, Gillet C .
  4. Web site: Pharma & Medteck Business Intelligence . 5 November 1984 . Monsanto's $150 mil. Life Sciences Research Center . https://web.archive.org/web/20150707040046/https://www.pharmamedtechbi.com/publications/the-pink-sheet/46/045/monsantos-150-mil-life-sciences-research-center . 2015-07-07 .
  5. Web site: Department of Economic and Social Affairs of the United Nations Secretariat . Consolidated List of Products Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted or not Approved by Governments Twelfth Issue: Pharmaceuticals . United Nations . New York . 2005 .

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