Sulbenicillin Explained

Sulbenicillin (INN) is a penicillin antibiotic, notable for its combination use with dibekacin. [1] Penicillins, crucial in primary healthcare for potent bactericidal properties and wide distribution, include oral options for enhanced accessibility. Post-World War II, synthetic penicillins like sulbenicillin broadened efficacy, leading to new groups that diversified treatment. This evolution reflects a dynamic interplay between science and clinical needs, emphasizing enduring value in managing infectious diseases in primary care.

Structure and mechanism of action

Characterized by a distinctive beta-lactam ring, penicillins inhibit bacterial cell wall synthesis, leading to cell destruction. This mechanism is effective against a broad spectrum of bacteria.[2]

Notes and References

  1. Aonuma S, Ariji F, Oizumi K, Konno K . June 1987 . Electron microscopy of Pseudomonas aeruginosa treated with sulbenicillin and dibekacin . Tohoku J. Exp. Med. . 152 . 2 . 119–28 . 10.1620/tjem.152.119 . 3114912 . free.
  2. Web site: PubChem . CID 5317 . 2023-12-20 . pubchem.ncbi.nlm.nih.gov . en.