Succinylornithine transaminase explained
| succinylornithine transaminase |
| Ec Number: | 2.6.1.81 |
| Go Code: | 0043825 |
| Width: | 270 |
In enzymology, a succinylornithine transaminase is an enzyme that catalyzes the chemical reaction
N2-succinyl-L-ornithine + 2-oxoglutarate
N-succinyl-L-glutamate 5-semialdehyde + L-glutamate
Thus, the two substrates of this enzyme are N2-succinyl-L-ornithine and 2-oxoglutarate, whereas its two products are N-succinyl-L-glutamate 5-semialdehyde and L-glutamate.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is N2-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase. Other names in common use include succinylornithine aminotransferase, N2-succinylornithine 5-aminotransferase, AstC, SOAT, and 2-N-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase. This enzyme participates in arginine and proline metabolism.
References
- Vander Wauven C, Stalon V . 1985 . Occurrence of succinyl derivatives in the catabolism of arginine in Pseudomonas cepacia . J. Bacteriol. . 164 . 882 - 6 . 2865249 . 2 . 214334 .
- Schneider BL, Kiupakis AK, Reitzer LJ . 1998 . Arginine catabolism and the arginine succinyltransferase pathway in Escherichia coli . J. Bacteriol. . 180 . 4278 - 86 . 9696779 . 16 . 107427 .
- Cunin R, Glansdorff N, Pierard A, Stalon V . 1986 . Biosynthesis and metabolism of arginine in bacteria . Microbiol. Rev. . 50 . 314 - 52 . 3534538 . 3 . 373073 .
- Itoh Y . 1997 . Cloning and characterization of the aru genes encoding enzymes of the catabolic arginine succinyltransferase pathway in Pseudomonas aeruginosa . J. Bacteriol. . 179 . 7280 - 90 . 9393691 . 23 . 179677 . 10.1128/jb.179.23.7280-7290.1997.
- Stalon V, Vander Wauven C, Momin P, Legrain C . 1987 . Catabolism of arginine, citrulline and ornithine by Pseudomonas and related bacteria . J. Gen. Microbiol. . 133 . 2487 - 95 . 3129535 . 9 . 10.1099/00221287-133-9-2487.
