| Subprefecture of Ermelino Matarazzo | |
| Settlement Type: | Subprefecture |
| Image Map1: | SaoPaulo Municip SaoPaulo.svg |
| Map Caption1: | Location of municipality of São Paulo within the State of São Paulo |
| Subdivision Type: | Country |
| Subdivision Name: |  Brazil |
| Subdivision Type1: | Region |
| Subdivision Name1: | Southeast |
| Subdivision Type2: | State |
| Subdivision Name2: | São Paulo |
| Subdivision Type3: | Municipality |
| Subdivision Name3: | São Paulo |
| Subdivision Type4: | Administrative Zone |
| Subdivision Name4: | East 1 |
| Parts Type: | Districts |
| Parts Style: | para |
| P1: | Ermelino Matarazzo |
| P2: | Ponte Rasa |
| Government Type: | Subprefecture |
| Leader Title: | Subprefect |
| Leader Name: | Antonio Sergio Palazzi |
| Area Total Km2: | 15.5 |
| Population Total: | 210,709 |
| Population As Of: | 2008 |
The Subprefecture of Ermelino Matarazzo is one of 32 subprefectures of the city of São Paulo, Brazil. It comprises two districts: Ermelino Matarazzo and Ponte Rasa.[1] It hosts the second largest campus of University of São Paulo in the city.