Stromelysin 2 Explained

Stromelysin 2
Ec Number:	3.4.24.22
Cas Number:	140610-48-6

Stromelysin 2 (matrix metalloproteinase 10, transin 2, proteoglycanase 2) is an enzyme.^{[1] [2] [3]} This enzyme catalyses the following chemical reaction

Similar to stromelysin 1, but action on collagen types III, IV and V is weak

This enzyme belongs to the peptidase family M10 (interstitial collagenase family).

Notes and References

1. Breathnach R, Matrisian LM, Gesnel MC, Staub A, Leroy P . Sequences coding for part of oncogene-induced transin are highly conserved in a related rat gene . Nucleic Acids Research . 15 . 3 . 1139–51 . February 1987 . 3547333 . 340513 . 10.1093/nar/15.3.1139 .
2. Muller D, Quantin B, Gesnel MC, Millon-Collard R, Abecassis J, Breathnach R . The collagenase gene family in humans consists of at least four members . The Biochemical Journal . 253 . 1 . 187–92 . July 1988 . 2844164 . 1149273 . 10.1042/bj2530187.
3. Nicholson R, Murphy G, Breathnach R . Human and rat malignant-tumor-associated mRNAs encode stromelysin-like metalloproteinases . Biochemistry . 28 . 12 . 5195–203 . June 1989 . 2548603 . 10.1021/bi00438a042 .