Streptogrisin A Explained

Streptogrisin A
Ec Number:	3.4.21.80
Cas Number:	55326-50-6

Streptogrisin A (Streptomyces griseus protease A, protease A, proteinase A, Streptomyces griseus proteinase A, Streptomyces griseus serine proteinase 3, Streptomyces griseus serine proteinase A) is an enzyme.^{[1] [2] [3] [4] [5]} This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with specificity similar to chymotrypsin

This enzyme is isolated from Streptomyces griseus.

Notes and References

1. Johnson P, Smillie LB . The disulfide bridge sequences of a serine protease of wide specificity from Streptomyces griseus . Canadian Journal of Biochemistry . 49 . 5 . 548–62 . May 1971 . 5575653 . 10.1139/o71-082 .
2. Sielecki AR, Hendrickson WA, Broughton CG, Delbaere LT, Brayer GD, James MN . Protein structure refinement: Streptomyces griseus serine protease A at 1.8 A resolution . Journal of Molecular Biology . 134 . 4 . 781–804 . November 1979 . 119870 . 10.1016/0022-2836(79)90486-8 .
3. James MN, Sielecki AR, Brayer GD, Delbaere LT, Bauer CA . Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 A resolution. A model for serine protease catalysis . Journal of Molecular Biology . 144 . 1 . 43–88 . November 1980 . 6783761 . 10.1016/0022-2836(80)90214-4 .
4. Delbaere LT, Brayer GD . The 1.8 A structure of the complex between chymostatin and Streptomyces griseus protease A. A model for serine protease catalytic tetrahedral intermediates . Journal of Molecular Biology . 183 . 1 . 89–103 . May 1985 . 3892018 . 10.1016/0022-2836(85)90283-9 .
5. Henderson G, Krygsman P, Liu CJ, Davey CC, Malek LT . Characterization and structure of genes for proteases A and B from Streptomyces griseus . Journal of Bacteriology . 169 . 8 . 3778–84 . August 1987 . 3112129 . 212465 .