| Country: | ITA |
| Regions: | Sardinia |
| Type: | SS |
| Route: | 125 |
| Map: | SS_125_percorso.png |
| Maint: | ANAS |
| Length Km: | 354.250 |
| Length Ref: | [1] |
| Established: | 1928 |
| Terminus A: | SS 554 at Quartucciu |
| Terminus B: | SS 133 at Palau |
Strada statale 125 Orientale Sarda (SS 125) is a national highway in Italy. It is the fastest and oldest connecting road in eastern Sardinia.