Stigmella desperatella is a moth of the family Nepticulidae. It is found from Estonia to the Pyrenees, Italy and Bulgaria, and from Great Britain to Ukraine.
The wingspan is 4–5 mm. Adults are on wing in June.
The larvae feed on Malus baccata, Malus domestica, Malus sylvestris and Pyrus communis. They mine the leaves of their host plant.