Steven E. Brenner Explained

Steven Brenner
Birth Name:	Steven Elliot Brenner
Doctoral Advisor:	Cyrus Chothia
Thesis Title:	Molecular propinquity: evolutionary and structural relationships of proteins
Thesis Url:	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596888
Thesis Year:	1996
Known For:	Structural Classification of Proteins
Awards:	Overton Prize (2010)^[1]

Steven Elliot Brenner is a professor at the Department of Plant and Microbial Biology at the University of California Berkeley, adjunct professor at the Department of Bioengineering and Therapeutic Sciences at the University of California, and San FranciscoFaculty scientist, Physical Biosciences at the Lawrence Berkeley National Laboratory.^[2] ^[3] ^[4]

Education

Brenner gained his Bachelor of Arts in 1992 from Harvard University and Doctor of Philosophy in 1997 from the University of Cambridge for research supervised by Cyrus Chothia.^[5] ^[6] He was one of the creators of the Structural Classification of Proteins (SCOP) database^[7] while working at the Laboratory of Molecular Biology (LMB) in Cambridge, UK.

Career and research

research in Brenner's laboratory investigates:

Individual genome interpretation^[2]
The regulation of gene expression by alternative splicing and nonsense-mediated decay of messenger RNA^[2]
Protein function prediction using Bayesian phylogenomics^[2]

Awards and honors

In 2010 he was awarded the Overton Prize from the International Society for Computational Biology.^[1] ^[8]

Notes and References

McKay . B. M. . Sansom . C. . 10.1371/journal.pcbi.1000831 . 2010 ISCB Overton Prize Awarded to Steven E. Brenner . . 6 . 6 . e1000831 . 2010 . 20585610. 2891695 . 2010PLSCB...6E0831M . free .
Web site: Brenner Laboratory: Computational Genomics Research Group. compbio.berkeley.edu. Steven. Brenner. 2017.
Brenner . Steven E.. Steven E. Brenner . Be prepared for the big genome leak: It is only a matter of time until idealism sees the release of confidential genetic data on study participants. 10.1038/498139a . Nature . 498 . 7453 . 139 . 2013 . 23765454. free .
Stajich . J. E. . Block . D. . Boulez . K. . Brenner . S.. Steven E. Brenner . Chervitz . S. . Dagdigian . C. . Fuellen . G. . Gilbert . J. . Korf . I. . Lapp . H. . Lehväslaiho . H. . Matsalla . C. . Mungall . C. J. . Osborne . B. I. . Pocock . M. R. . Schattner . P. . Senger . M. . Stein . L. D. . Lincoln Stein. Stupka . E. . Wilkinson . M. D. . Birney . E. . Ewan Birney. The BioPerl Toolkit: Perl Modules for the Life Sciences . 10.1101/gr.361602 . Genome Research . 12 . 10 . 1611–1618 . 2002 . 12368254 . 187536 .
PhD. Steven Elliot. Brenner. Molecular propinquity: evolutionary and structural relationships of proteins. University of Cambridge. 1996. . lib.cam.ac.uk. 879392272.
Web site: About Steven E. Brenner. compbio.berkeley.edu.
Murzin . A. G. . Brenner . S. . Steven E. Brenner . Hubbard . T. . Tim Hubbard . Chothia . C. . Cyrus Chothia . SCOP: A structural classification of proteins database for the investigation of sequences and structures . . 247 . 4 . 536–540 . 1995 . 10.1016/S0022-2836(05)80134-2 . 7723011 . dead . https://web.archive.org/web/20120426170732/http://scop.mrc-lmb.cam.ac.uk/scop/ref/1995-jmb-scop.pdf . 2012-04-26.
Web site: Overton Prize winners.