| Office: | Member of Parliament for Akan constituency |
| Alma Mater: | Achimota School and University of Ghana |
| Honorific Prefix: | Hon. |
| Birth Date: | 24 May 1937 |
| Occupation: | Politician |
| Profession: | Lawyer |
| Termend: | 13 January 1972 |
| Termstart: | 1 October 1969 |
| Party: | National Alliance of Liberals |
Stephen Kwadwo Osei-Nyame is a Ghanaian politician and member of the first parliament of the second republic of Ghana representing Akan constituency in the Volta Region of Ghana under the membership of the National Alliance Liberals (NAL)[1]
Osei-Nyame was born on 24 May 1937. He attended Achimota School and the University of Ghana where he obtained Bachelor of Arts and bachelor of laws degree.
Osei-Nyame worked as a lawyer before going into Parliament. He began his political career in 1969 when he became the parliamentary candidate to represent Akan constituency in the Volta Region of Ghana prior to the commencement of the 1969 Ghanaian parliamentary election.[2]
He was sworn into the First Parliament of the Second Republic of Ghana on 1 October 1969, after being pronounced winner at the 1969 Ghanaian election held on 26 August 1969. and his tenure of office ended on 13 January 1972.[3]
He is a Christian.