| Stephen Holbrook Rhodes | |
| Term Start: | June 19, 1867 |
| Term End: | 1870 |
| Birth Date: | November 7, 1825 |
| Death Place: | Brookline, Massachusetts |
| Office2: | Member of the Massachusetts State Senate |
| Term Start2: | 1870 |
| Term End2: | 1871 |
| Office3: | Member of the Taunton, Massachusetts Board of Aldermen Ward One |
| Term Start3: | 1867 |
| Term End3: | June 19, 1867 |
| Predecessor3: | Edgar H. Reed |
| Successor3: | Abram Biggs |
| Office4: | 4th President of The John Hancock Mutual Life Insurance Company. |
| Term Start4: | March 1879 |
| Term End4: | June 11, 1909 |
| Predecessor4: | George Thornton |
| Successor4: | Roland O. Lamb |
| Title5: | 11th Insurance Commissioner of Massachusetts |
| Term Start5: | December 8, 1874 |
| Term End5: | March 12, 1879 |
| Successor5: | Julius L. Clarke |
| Spouse: | E. M. Godfry |
| Signature: | Signature of Stephen Holbrook Rhodes.png |
Stephen Holbrook Rhodes (November 7, 1825 – June 11, 1909) was a Massachusetts businessman and politician who served in the Massachusetts Senate, as the second Mayor of Taunton, Massachusetts, and as the fourth President of The John Hancock Mutual Life Insurance Company.
Rhodes was born in Franklin, Massachusetts, on November 7, 1825, to Stephen and Betsy (Bird) Rhodes.
Rhodes married E. M. Godfry in Taunton, Massachusetts, on November 27, 1847.
Rhodes died on June 11, 1909, at his home in Brookline, Massachusetts.