Stephen Friend Explained

Stephen H. Friend is co-founder and director of Sage Bionetworks.^{[1] [2] [3]}

Formerly Senior Vice-president at Merck & Co. Friend co-founded Rosetta Inpharmatics with Leland H. Hartwell and Leroy Hood in 1996.^[4] Much of his research has focused on cancer.^[5]

Friend has also held faculty positions at Harvard Medical School and at Massachusetts General Hospital. He received his Bachelor of Arts in philosophy, his Ph.D. in biochemistry and his M.D. from Indiana University.^[2]

Recognition

Friend is named an Ashoka Fellow by in 2011.^[6]

Selected bibliography

• 17000754. 1698535. 2006. Bartz. S. R.. Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions. Molecular and Cellular Biology. 26. 24. 9377–86. Zhang. Z. Burchard. J. Imakura. M. Martin. M. Palmieri. A. Needham. R. Guo. J. Gordon. M. Chung. N. Warrener. P. Jackson. A. L.. Carleton. M. Oatley. M. Locco. L. Santini. F. Smith. T. Kunapuli. P. Ferrer. M. Strulovici. B. Friend. S. H.. Linsley. P. S.. 10.1128/MCB.01229-06.
• 16477019. 1413797. 2006. Radich. J. P.. Gene expression changes associated with progression and response in chronic myeloid leukemia. Proceedings of the National Academy of Sciences. 103. 8. 2794–9. Dai. H. Mao. M. Oehler. V. Schelter. J. Druker. B. Sawyers. C. Shah. N. Stock. W. Willman. C. L.. Friend. S. Linsley. P. S.. 10.1073/pnas.0510423103. 2006PNAS..103.2794R. free.
• 15899795. 2005. Dai. H. A cell proliferation signature is a marker of extremely poor outcome in a subpopulation of breast cancer patients. Cancer Research. 65. 10. 4059–66. Van't Veer. L. Lamb. J. He. Y. D.. Mao. M. Fine. B. M.. Bernards. R. Van De Vijver. M. Deutsch. P. Sachs. A. Stoughton. R. Friend. S. 10.1158/0008-5472.CAN-04-3953. free.
• 15006922. 2004. Lampe. J. W.. Signatures of environmental exposures using peripheral leukocyte gene expression: Tobacco smoke. Cancer Epidemiology, Biomarkers & Prevention. 13. 3. 445–53. Stepaniants. S. B.. Mao. M. Radich. J. P.. Dai. H. Linsley. P. S.. Friend. S. H.. Potter. J. D.. 10.1158/1055-9965.445.13.3. 7624677. free.
• 12559048. 154139. 2003. Van 't Veer. L. J.. Expression profiling predicts outcome in breast cancer. Breast Cancer Research. 5. 1. 57–8. Dai. H. Van De Vijver. M. J.. He. Y. D.. Hart. A. A.. Bernards. R. Friend. S. H.. 10.1186/bcr562. free.
• 12490681. 2002. Van De Vijver. M. J.. A gene-expression signature as a predictor of survival in breast cancer. New England Journal of Medicine. 347. 25. 1999–2009. He. Y. D.. Van't Veer. L. J.. Dai. H. Hart. A. A.. Voskuil. D. W.. Schreiber. G. J.. Peterse. J. L.. Roberts. C. Marton. M. J.. Parrish. M. Atsma. D. Witteveen. A. Glas. A. Delahaye. L. Van Der Velde. T. Bartelink. H. Rodenhuis. S. Rutgers. E. T.. Friend. S. H.. Bernards. R. 10.1056/NEJMoa021967. 1874/15577. free.
• 21750698. 3130029. 2011. Lamb. J. R.. Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting. PLOS ONE. 6. 7. e20090. Zhang. C. Xie. T. Wang. K. Zhang. B. Hao. K. Chudin. E. Fraser. H. B.. Millstein. J. Ferguson. M. Suver. C. Ivanovska. I. Scott. M. Philippar. U. Bansal. D. Zhang. Z. Burchard. J. Smith. R. Greenawalt. D. Cleary. M. Derry. J. Loboda. A. Watters. J. Poon. R. T.. Fan. S. T.. Yeung. C. Lee. N. P.. Guinney. J. Molony. C. Emilsson. V. 29. 10.1371/journal.pone.0020090. 2011PLoSO...620090L. free.
• 12097304. 2002. Mihich. E. Thirteenth annual pezcoller symposium: Focusing analytical tools on complexity in cancer. Cancer Research. 62. 13. 3883–7. Feunteun. J. Friend. S.

External links

• TED talk with Stephen Friend

Notes and References

1. 10.1126/science.335.6069.651. 22323794. The Visionary. Science. 335. 6069. 651–3. 2012. Kaiser. J..
2. Web site: Sage Bionetworks Seattle | Directors . https://web.archive.org/web/20120127081638/http://sagebase.org/info/directors.php . 2012-01-27 . 2012-02-11 . dead .
3. 10.1038/nrd2509. Stephen Friend. Nature Reviews Drug Discovery. 7. 2. 114. 2008. free.
4. 10.1038/458013a. 19262635. Something wiki this way comes. Nature. 458. 7234. 13. 2009. Nelson. Bryn. Schadt. E. free.
5. 10.1126/science.335.6069.651 . 22323794 . The Visionary . Science . 335 . 6069 . 651–3 . 2012 . Kaiser . J. .
6. http://sagebase.org/info/NewsInfoDownloads/SageAshokaRelease6APR2011.pdf{{Dead link|date=August 2017}}