Stephanie Cragg Explained

Stephanie J. Cragg is a British physiologist who is Professor of Neuroscience at the University of Oxford.^[1] She holds a joint appointment^[2] as Professor in the University Department of Physiology, Anatomy and Genetics and as a Fellow, Director of Studies and Tutor for Medicine at the college Christ Church, Oxford.^[3]

Education and awards

Cragg studied Natural Sciences at Clare College, University of Cambridge, followed by a DPhil in neuropharmacology at the University of Oxford Department of Pharmacology.^[2] Her graduate supervisors were Baroness Professor Susan Greenfield (Oxford) and Dr Margaret Rice (New York University).^[4] She received postdoctoral awards of an E.P. Abraham Junior Research Fellowship at St. Cross College, an E.P. Abraham Research Fellowship at Keble College, a Beit Memorial Fellowship and then a Paton Research Fellowship.^[2]

Research

Her work focusses on understanding the functioning in health and disease of the brain circuits and cell types that are dysregulated in Parkinson's disease, addictions and other neurological and neuropsychiatric disorders.^{[3] [5]} This work focusses particularly on the regulation of dopaminergic transmission.

Cragg's work includes the study of how dopamine release in the striatum is regulated by other neuronal pathways and neuromodulators, including the neurotransmitters acetylcholine, GABA, adenosine, and dysregulation in Parkinson's disease.^{[6] [7]} Her most cited work relates to the axonal regulation of dopamine transmission by acetylcholine, cholinergic interneurons and nicotinic acetylcholine receptors (nAChRs).^{[8] [9]}

Scientific leadership

Scientific journals

• Addiction Neuroscience^[10]
• ACS Chemical Neuroscience^[11]
• npj Parkinson's Disease^[12]

Societies

Engagement with scientific societies include:

• President-Elect of the International Society for Monitoring Molecules in Neuroscience (2022-2024)^[13]
• College of Experts for Parkinson's UK^[14]

Keynote lectures

• EJN Special Feature Plenary Lecture, FENS Forum 2018, Berlin, Germany^[15]
• Keynote Speaker, ViDA 2020 - Virtual Dopamine Conference^[16]
• Swedish Basal Ganglia Society 2022^[17]
• Plenary Lecture, Dopamine 2022, Montreal, Canada^[18]

External links

• Pubmed reference list

Notes and References

1. https://www.ox.ac.uk/gazette/2014-2015/6november2014-no5076/notices/#174327 "Recognition of Distinction: Successful applicants 2014"
2. Web site: Stephanie Cragg . www.dpag.ox.ac.uk . 18 October 2023 . en.
3. Web site: Professor Stephanie Cragg Christ Church, University of Oxford . www.chch.ox.ac.uk . 18 October 2023 . en.
4. Helmreich . Dana L. . Profiles of Women in Science: Prof. Stephanie Cragg of the University of Oxford, Oxford, UK . European Journal of Neuroscience . 18 October 2023 . 1723–1727 . en . 10.1111/ejn.14058 . July 2018. 48 . 2 . 29968289 .
5. Web site: Stephanie Cragg . www.dpag.ox.ac.uk . 18 October 2023 . en.
6. Roberts . Bradley M. . Doig . Natalie M. . Brimblecombe . Katherine R. . Lopes . Emanuel F. . Siddorn . Ruth E. . Threlfell . Sarah . Connor-Robson . Natalie . Bengoa-Vergniory . Nora . Pasternack . Nicholas . Wade-Martins . Richard . Magill . Peter J. . Cragg . Stephanie J. . GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model . Nature Communications . 2 October 2020 . 11 . 1 . 4958 . 10.1038/s41467-020-18247-5. free . 33009395 . 7532441 . 2020NatCo..11.4958R .
7. Cramb . Kaitlyn M L . Beccano-Kelly . Dayne . Cragg . Stephanie J . Wade-Martins . Richard . Impaired dopamine release in Parkinson's disease . Brain . 1 August 2023 . 146 . 8 . 3117–3132 . 10.1093/brain/awad064. free . 36864664 . 10393405 .
8. Threlfell . Sarah . Lalic . Tatjana . Platt . Nicola J.. Jennings . Katie A.. Deisseroth . Karl . Cragg . Stephanie J.. Striatal Dopamine Release Is Triggered by Synchronized Activity in Cholinergic Interneurons . Neuron . July 2012 . 75 . 1 . 58–64 . 10.1016/j.neuron.2012.04.038. free . 22794260 .
9. Rice . Margaret E . Cragg . Stephanie J . Nicotine amplifies reward-related dopamine signals in striatum . Nature Neuroscience . June 2004 . 7 . 6 . 583–584 . 10.1038/nn1244. 15146188 .
10. Web site: Addiction Neuroscience Journal ScienceDirect.com by Elsevier . www.sciencedirect.com . en-us.
11. Web site: Editors & Editorial Board . ACS Publications.
12. Web site: npj Parkinson's Disease . Nature . 18 October 2023 . en . 10 July 2023.
13. Web site: About . MMiN . 18 October 2023.
14. Web site: Parkinson's UK College of Experts . Parkinson's UK . 18 October 2023 . en.
15. Web site: Feature Plenary Lecture, FENS Forum 2018 .
16. Web site: Speakers . VIDA 2020 . en.
17. Web site: Webinar Recordings .
18. Web site: Plenary Lectures .