Stemar-13-ene synthase explained

Stemar-13-ene synthase
Ec Number:	4.2.3.33

Stemar-13-ene synthase (EC 4.2.3.33, OsDTC2, OsK8, OsKL8, OsKS8, stemarene synthase, syn-stemar-13-ene synthase) is an enzyme with systematic name 9α-copalyl-diphosphate diphosphate-lyase (stemar-13-ene-forming).^{[1] [2]} This enzyme catalyses the following chemical reaction

9α-copalyl diphosphate

\rightleftharpoons stemar-13-ene + diphosphate

This diterpene cyclase produces stemar-13-ene, a putative precursor of the rice phytoalexin oryzalexin S.

Notes and References

1. Mohan RS, Yee NK, Coates RM, Ren YY, Stamenkovic P, Mendez I, West CA . Biosynthesis of cyclic diterpene hydrocarbons in rice cell suspensions: conversion of 9,10-syn-labda-8(17),13-dienyl diphosphate to 9beta-pimara-7,15-diene and stemar-13-ene . Archives of Biochemistry and Biophysics . 330 . 1 . 33–47 . June 1996 . 8651702 . 10.1006/abbi.1996.0223 .
2. Nemoto T, Cho EM, Okada A, Okada K, Otomo K, Kanno Y, Toyomasu T, Mitsuhashi W, Sassa T, Minami E, Shibuya N, Nishiyama M, Nojiri H, Yamane H . Stemar-13-ene synthase, a diterpene cyclase involved in the biosynthesis of the phytoalexin oryzalexin S in rice . FEBS Letters . 571 . 1-3 . 182–6 . July 2004 . 15280039 . 10.1016/j.febslet.2004.07.002 . free .