Stefan H. E. Kaufmann Explained

Stefan H.E. Kaufmann
Birth Date:8 June 1948
Birth Place:Ludwigshafen am Rhein, Germany
Nationality:German
Workplaces:University of Ulm
Max Planck Institute for Infection Biology, Berlin
Alma Mater:University of Mainz, 1977
Free University Berlin, 1981
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Known For:Immunology
Microbiology
Awards:Gagna A. & Ch. Van Heck Prize (2018)
Spouse:Elke Kaufmann
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Children:2

Stefan Hugo Ernst Kaufmann (born 8 June 1948 in Ludwigshafen am Rhein) is a German immunologist and microbiologist and is one of the highly cited immunologists worldwide for the decade 1990 to 2000.[1] He is amongst the 0.01% most cited scientists of 7 million scientists in 22 major scientific fields globally.[2]

Biography

Kaufmann is a German immunologist and microbiologist with focus on infection biology. He received his Dr. Rer. Nat. (PhD) at the University of Mainz in 1977 and his habilitation in immunology and microbiology at the Free University Berlin in 1981. He was professor at the University of Ulm from 1987 to 1998. Currently, he is director of the Department of Immunology at the Max Planck Institute for Infection Biology in Berlin, for which he served as founding director in 1993. Since 2019 he is director emeritus at this institute and leader of an emeritus group on systems immunology at the Max Planck Institute for Multidisciplinary Sciences. Member of the Max Planck Society since 1993. Since 1998 he is also professor for immunology and microbiology at the Charité Berlin. Since 2018 he is faculty fellow of the Hagler Institute for Advanced Study at Texas A&M University https://hias.tamu.edu/. He was appointed Senior Professor at Charité – Universitätsmedizin Berlin in September 2022.

Kaufmann collects historical medicinal books.[3]

Career

Kaufmann has published more than 1000 scientific original papers and review articles and according to the Clarivate – Web of Science, Highly Cited Researcher (category Immunologie) 2001,[4] Highly Cited Researcher (category Cross-Field) 2020 [5] he is one of the highly cited immunologists and vaccinologists with more than 99,000 citations (Google Scholar) worldwide for the decade 1990 to 2000 and has an h-index of >155 (as of October 2021). Immunology Leader Award for 2023, and Medicine Leader Award for 2023, Germany (Research.com) https://research.com/. His current scientific interest is focused on the analysis of cell-mediated immunity against intracellular bacteria, the rational design and development of a better vaccine against tuberculosis as well as of biomarkers for reliable diagnosis of TB disease. Biomarker discovery is done in a multicentric approach with seven partner institutes in Africa with support from the Bill and Melinda Gates Foundation.[6] [7] His vaccine against tuberculosis is currently in phase III clinical trial assessment.[8] [9] [10] [11] A phase III vaccine trial to test prevention of tuberculosis recurrence (NCT 03152903)[12] [13] and a phase III trial to test prevention of tuberculosis disease in household contacts of tuberculosis patients are ongoing in India (CTRI/2019/01/017026).[14] A third phase III trial to assess protection against tuberculosis in neonates (priMe) is currently ongoing at nine trial sites in five Sub-Saharan African countries (NCT 04351685) with financial support from the European Investment Bank.[15] Moreover, a clinical study assessing therapy of bladder cancer with the vaccine has revealed highly promising data (NCT 02371447).[16] Another clinical study tested heterologous protection against SARS-CoV-2 and Covid-19 by the vaccine (NCT 04435379).[17] Furthermore, Kaufmann is actively involved in public awareness of immunology and infectious diseases (EFIS – Day of Immunology).[18] In his recent books written in German, he has answered questions on Covid-19 [19] and vaccination [20] in a detailed and comprehensible manner.

He is past president and honorary member of the German Society of Immunology (DGfI)https://dgfi.org/, past president of the European Federation of Immunological Societies (EFIS)https://www.efis.org/,[21] [22] and past president of the International Union of Immunological Societies (IUIS)http://www.iuisonline.org.[23] From 2010 to 2013 he was member of the board of the Global Alliance for Vaccines and Immunization (GAVI) https://www.gavi.org/ as alternate representative of scientific and technical institutes. From 2009 to 2014 he was a member of the advisory board of Global Alliance for TB Drug Development (TB Alliance) https://www.tballiance.org/, New York. From 2014 to 2018 he was member of the strategic advisory committee of the European and Developing Countries Clinical Trials Partnership (EDCTP) http://www.edctp.org/. Kaufmann was member of the board of directors from 2003 to 2019 and of the scientific advisory council from 1998 to 2017 of the Robert Koch Foundation, which annually awards the Robert Koch Prize and the Robert Koch Medal in gold. From 2014 to 2023 he was chairman of the board of trustees of the Schering Foundation. From 2013 to 2014 he was corresponding member of the board of trustees and since 2014 he is full member of the board of trustees for the Lindau Nobel Laureate meetings for the Lindau Nobel Laureate Meetings.[24] Since 2018 he is member of the Governance Board of the TuBerculosis Vaccine Initiative (TBVI) https://www.tbvi.eu/about-us/organisation/governance-board/.

Kaufmann headed a team that developed a method of using defensins to combat anthrax.[25]

Other activities

Prizes and honours

Kaufmann has received numerous rewards and honours for his scientific achievements in immunology of infectious diseases including:

In 2007, Kaufmann was conferred the title of Doctor Honoris Causa by the Université de la Mediterranée, Aix-Marseille II, France. In 2014 he received the Gardner Middlebrook Award. From 2014 to 2021, he was Fellow of the Royal College of Physicians of Edinburgh (FRCP Edin). He is Guest Professor, Tongji University, School of Medicine, Shanghai, China (since 2011), Honorary Professor, Universidad Peruana Cayetano Heredia, Lima, Peru (since 2012), and Visiting Professor, Peking Union Medical College, Beijing, China (since 2014).

Partial bibliography

External links

Videos

Latest Thinking: https://lt.org/publication/can-biosignatures-be-used-develop-reliable-fast-and-low-cost-test-tuberculosis

Latest Thinking: https://lt.org/publication/how-can-we-improve-existing-vaccine-tuberculosis-combat-growing-number-multi-resistant

Notes and References

  1. According to the Institute for Scientific Information
  2. PLoS Biol 17(8): e3000384, 2019
  3. Neugier und Bazillen, Cicero Magazin (Sabine Rosenbladt), p. 136-139, January 2011
  4. Web site: World's largest publisher-neutral citation index and research intelligence platform. Web of Science Group. 26 November 2021.
  5. Web site: Stefan HE Kaufmann's Publons profile. publons.com. 26 November 2021.
  6. Global Commitment of Max Planck Researchers . Max Planck Society . 2005-06-28 . 2010-06-19.
  7. http://insciences.org/article.php?article_id=9982 Insciences
  8. Web site: Clinical trial for new tuberculosis vaccine . Max Planck Society . 2008-09-11 . 2010-06-19.
  9. Rational Vaccine Development – A New Trend in Tuberculosis Control . 10.1056/NEJMcibr053426 . The New England Journal of Medicine . 2005-10-13 . Gilla Kaplan, Ph.D. . 353 . 15 . 2010-06-19 . New England Journal of Medicine . 1624–1625. 16221789 .
  10. 10.1126/science.334.6062.1488 . Taking a New Shot at a TB Vaccine . 2011 . Kupferschmidt . K. . Science . 334 . 6062 . 1488–90 . 22174226 . 2011Sci...334.1488K .
  11. Spritze gegen Schwindsucht, Der Spiegel 20/2012, Medizin, S. 118, 2012
  12. http://www.thehindu.com/todays-paper/tp-national/tb-vaccine-trial-on-adults-begins-in-june/article17741109.ece TB vaccine trial on adults begins in June.
  13. http://www.thehindu.com/opinion/op-ed/new-bcgbased-tb-vaccine-revamped-safer-and-with-greater-punch/article8262023.ece?topicpage=true&topicId=2045 Revamped, safer, and with greater punch.
  14. https://www.thehindubusinessline.com/news/science/icmr-launches-tb-vaccine-trial/article28437538.ece ICMR begins trials on vaccine for close contacts of TB patients.
  15. https://www.vpm-consult.com/de/news-events/news/update-zur-prime-studie, 1 February 2019
  16. Web site: Modified tuberculosis vaccine as therapy against bladder cancer . mpiib-berlin.mpg.de . February 20, 2020.
  17. https://academic.oup.com/cid/article/76/7/1304/6821343 Against Severe Respiratory Tract Infections Including COVID-19 in the Elderly: a phase III randomised, double-blind, placebo-controlled, multicenter clinical study.
  18. How pandemics happen. Megan Murray, Nature Medicine, Book Review, Vol. 16 | No. 2 | February 2010, p. 159
  19. "Covid-19 und die Bedrohungen durch Pandemien". Available for free at: https://hlz.hessen.de/publikationen/publikation/?id=cba0b1d5-72a7-4fd6-a1d8-5573e205d09d
  20. "Impfen. Grundlagen, Wirkung, Risiken". C.H. Beck Verlag. ISBN 978-3-406-77144-6.https://www.beck-shop.de/kaufmann-h-e-impfen/product/32309246
  21. Web site: EFIS – European Federation of Immunological Societies . 2011-08-23 . 2012-03-31 . https://web.archive.org/web/20120331030455/http://www.immunology-info.org/index.php?filmid=0&play=true#projector . dead .
  22. Web site: EFIS – European Federation of Immunological Societies. www.efis.org. 26 November 2021.
  23. Web site: IUIS » International Union of Immunological Societies. IUIS. 26 November 2021.
  24. http://www.sueddeutsche.de/wissen/portraet-mut-etwas-zu-machen-1.4024348/ "Portraet – Mut, etwas zu machen"
  25. Max Planck Society (2005, April 1). Defensins Neutralize Anthrax Toxin. ScienceDaily. Retrieved May 25, 2010, from Science Daily News
  26. https://www.worldhealthsummit.org/about-whs/leadership.html Council
  27. News: About. The Lindau Nobel Laureate Meetings. 2018-09-17. en-US.
  28. Web site: Van Heck Prize für Stefan Kaufmann . Nationale Akademie der Wissenschaften Leopoldina . 25 September 2021 . de . 26 November 2021.
  29. Web site: GAGNA A. & Ch. VAN HECK Prize – 2018 . Max Planck Institute for Infection Biology . 4 October 2021 . 26 November 2021.
  30. https://www.mpiib-berlin.mpg.de/2285/en Ernst Hellmuth Vits Prize- 2022