| State: | VA |
| Type: | VA |
| Route: | 121 |
| Alternate Name: | Max Meadows Road |
| Length Mi: | 1.83 |
| Length Round: | 2 |
| Map: | VA 121 map.svg |
| Established: | 1933 |
| Tourist: | Virginia Byway |
| Direction A: | South |
| Direction B: | North |
| Terminus A: | at Fort Chiswell |
| Terminus B: | in Max Meadows |
| Counties: | Wythe |
| Previous Type: | US |
| Previous Route: | 121 |
| Next Type: | VA |
| Next Route: | 122 |
State Route 121 is a state highway in the U.S. state of Virginia. Known as Max Meadows Road, the state highway runs 1.83miles from Interstate 77, I-81, U.S. Route 11, and US 52 at Fort Chiswell north to SR 1004 and SR 1006 in Max Meadows in eastern Wythe County.
SR 121 is part of a Virginia Byway that continues south along US 52 and west along SR 610 to Wytheville.
SR 121 begins at a diamond interchange with I-77, I-81, and US 11 a short distance west of the interchange where I-77 turns south toward Charlotte and I-81 and US 11 continue east toward Roanoke. US 52 runs concurrently with the three other highways west to Wytheville and heads south from the interchange as Fort Chiswell Road toward Hillsville. SR 121 starts as a four-lane divided highway within the interchange but immediately reduces to a two-lane undivided road to head north to Max Meadows. The state highway crosses Reed Creek before entering the village, where it reaches its northern terminus at its intersection with SR 1004 (Ayers Street) and SR 1006 (Max Meadows Road) immediately to the north of its grade crossing of Norfolk Southern Railway's Pulaski District rail line and one block south of SR 610 (Peppers Ferry Road).
SR 121 was numbered in the 1933 renumbering as an extension of U.S. Route 121 (now US 52 south of Fort Chiswell). From 1931, when it was added to the state highway system, until 1933, SR 121 was part of the longer State Route 15, which also continued south on present US 52.