| State: | TX |
| Type: | SH |
| Route: | 65 |
| Map Custom: | yes |
| Length Mi: | 15.495 |
| Established: | 1961 |
| Direction A: | West |
| Direction B: | East |
| Terminus A: | near Anahuac |
| Terminus B: | at Stowell |
| Counties: | Chambers |
| Previous Type: | SH |
| Previous Route: | 64 |
| Next Type: | US |
| Next Route: | 66 |
State Highway 65 (SH 65) is a Texas state route that runs for 15.495miles within Chambers County, from near Anahuac to Stowell. This route was designated on December 30, 1961, replacing a portion of SH 73 identified as SH 73-T.
SH 65 was originally designated on August 21, 1923 along a route from Mt. Pleasant to Gladewater, replacing part of SH 11.[1] On September 26, 1939, this route was cancelled as it was part of U.S. Highway 271, which it was cosigned with since 1935.