The Staphylococcaceae are a family of Gram-positive bacteria that includes the genus Staphylococcus, noted for encompassing several medically significant pathogens.
The five genera Jeotgalicoccus, Macrococcus, Nosocomiicoccus, Salinicoccus, and Staphylococcus have been shown to be monophyletic, while Gemella appears to be polyphyletic. The pathogen methicillin-resistant Staphylococcus aureus is a member of this family.
The most famous species in this family is Staphylococcus aureus, usually found in the skin microbiota. Staphylococcus aureus is the pathogenic bacteria with the highest global mortality in 2019, with approximatively 1.1 million deaths.[1]