| Official Name: | St. Thomas, Minnesota |
| Settlement Type: | Unincorporated community |
| Pushpin Map: | Minnesota#USA |
| Pushpin Label: | St. Thomas |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Minnesota |
| Subdivision Type2: | County |
| Subdivision Name2: | Le Sueur |
| Subdivision Type3: | Township |
| Subdivision Name3: | Derrynane |
| Timezone: | Central (CST) |
| Utc Offset: | -6 |
| Timezone Dst: | CDT |
| Utc Offset Dst: | -5 |
| Elevation Ft: | 1004 |
| Coordinates: | 44.4978°N -93.7575°W |
| Postal Code Type: | ZIP code |
| Postal Code: | 56058 |
| Area Code: | 507 |
| Blank Name: | GNIS feature ID |
| Blank Info: | 651065 |
St. Thomas is an unincorporated community in Derrynane Township, Le Sueur County, Minnesota, United States.
The community is located along Le Sueur County Road 28 (St. Thomas Road) near its junction with Le Sueur County Road 11.
St. Thomas is located within ZIP code 56058 based in Le Sueur. Nearby places include Le Sueur, Lexington, Le Center, Heidelberg, Belle Plaine, Henderson, and St. Thomas Wildlife Management Area.
The community had a post office from 1872 to 1902, and a station on the former Chicago, St. Paul, Minneapolis and Omaha Railway.