| St. Nicholas Byzantine Catholic Church | |
| Location: | 504 S. Liberty St., Perryopolis, Pennsylvania |
| Coordinates: | 40.0819°N -79.7522°W |
| Built: | 1912-1918 |
| Architecture: | Byzantine Revival |
| Added: | November 7, 1997 |
| Area: | less than one acre |
| Refnum: | 97001247 |
St. Nicholas Byzantine Catholic Church, also known as St. Nicholas Greek Catholic Church, is a historic Catholic Church church at 504 S. Liberty Street in Perryopolis, Fayette County, Pennsylvania. It was built between 1912 and 1918, and is a 30 feet by 60 feet yellow brick building in the Byzantine Revival style. It has a cruciform plan and the gabled roof is topped by four onion domes. The church served a community of Rusyns who originally settled in the area prior to 1907.[1]
It was added to the National Register of Historic Places in 1997.