| St. Mary's High School | |
| Motto: | A Catholic, college-prep family since 1885 |
| Address: | 2501 East Yampa Street |
| City: | Colorado Springs |
| State: | Colorado |
| Zipcode: | 80909 |
| Country: | United States |
| Coordinates: | 38.8464°N -104.7842°W |
| Schooltype: | Private high school |
| Religious Affiliation: | Roman Catholicism |
| Ceeb: | 060295 |
| Principal: | Robyn Cross[1] |
| Teaching Staff: | 21.5 |
| Grades: | 9–12 |
| Enrollment: | 251 |
| Enrollment As Of: | 2017–18 |
| Ratio: | 11.7 |
| Colors: | Kelly green and white |
| Athletics Conference: | CHSAA |
| Mascot: | Pirate |
| Affiliation: | National Catholic Educational Association |
St. Mary's High School (SMHS) is a private, Roman Catholic high school located in the Roman Catholic Diocese of Colorado Springs, Colorado, United States. St. Mary's colors are kelly green and white, and its mascot is the Pirate.