| St. Mary’s Malankara Syrian Catholic Cathedral, Pattom, Trivandrum | |
| Denomination: | Syro-Malankara Catholic Church |
| Religious Institute: | The Syro-Malankara Catholic Church |
| Diocese: | Syro-Malankara Catholic Major Archeparchy of Trivandrum |
| Founded Date: | 1950 |
| Founder: | Metropolitan Archbishop Mar Ivanios |
| Style: | Baroque |
| Dedicated Date: | 22 February 1965 |
| Priest: | Fr. Dr. George Thomas, Fr. Varghese Malayil |
| Location: | Pattom, Trivandrum - 695 004, Kerala |
| Country: | India |
| Coordinates: | 8.5261°N 76.9381°W |
| Vicar: | Fr. Dr. George Thomas |
St. Mary's Malankara Syrian Catholic Cathedral, Pattom, Trivandrum is the central place of worship of the Syro-Malankara Catholic Church. It is the seat of the Major Archbishop of Trivandrum. The tombs of the Servant of God Archbishop Geevarghese Mar Ivanios, Archbishop Benedict Mar Gregorios and of Major Archbishop Cyril Baselios Catholicos are located here.
The foundation stone of this cathedral was laid by Archbishop Mar Ivanios in 1950, and the cathedral was consecrated by Archbishop Benedict Mar Gregorios on 22 February 1965.
Pope John Paul II visited the cathedral on 8 February 1986.
The cathedral was renovated in 2008. The blessing of the renovated cathedral was on 8 November 2008. There were 531 families in the parish community.