| Official Name: | St. Francisville, Missouri |
| Settlement Type: | Census-Designated Place |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Missouri |
| Subdivision Type2: | County |
| Subdivision Name2: | Clark |
| Unit Pref: | Imperial |
| Area Footnotes: | [1] |
| Area Total Km2: | 4.95 |
| Area Land Km2: | 4.81 |
| Area Water Km2: | 0.14 |
| Area Total Sq Mi: | 1.91 |
| Area Land Sq Mi: | 1.86 |
| Area Water Sq Mi: | 0.05 |
| Population As Of: | 2020 |
| Population Total: | 137 |
| Population Density Km2: | 28.46 |
| Population Density Sq Mi: | 73.70 |
| Elevation Ft: | 633 |
| Coordinates: | 40.4497°N -91.5719°W |
| Postal Code Type: | ZIP code |
| Postal Code: | 63472[2] |
| Area Code: | 660 |
| Blank Name: | FIPS code |
| Blank Info: | 29-64244 |
| Blank1 Name: | GNIS feature ID |
| Blank1 Info: | 2587112 |
St. Francisville or Saint Francisville is an unincorporated community and census-designated place in northeast Clark County, Missouri, United States. As of the 2020 census, its population was 137.[3]
The community is on Missouri Route B four miles north of Wayland. The Des Moines River and the Missouri-Iowa border are one-half mile north of the community.[4] It is the oldest settlement in Clark County, Missouri.
St. Francisville was platted in 1833, by a man named Francis Church.[5]