| St. Francis Xavier College | |
| Native Name: | Colégio São Francisco Xavier |
| Address: | Moreira and Costa Street, 531 |
| City: | Subprefecture of Ipiranga, São Paulo |
| State: | São Paulo |
| Country: | Brazil |
| Coordinates: | -23.5891°N -46.6089°W |
| Type: | Private primary and secondary school |
| Founder: | Guido del Toro |
| Gender: | Coeducational |
| Denomination: | Jesuit |
| Religion: | Catholic |
| Rector: | Eduardo Beltramini |
| Director: | Reinaldo Correa de Aquino Jr. |
| Teaching Staff: | 62 |
| Enrollment: | 1,219 |
| Grades: | K-12 |
| Former Name: | Japanese Catholic College of St. Francis Xavier |
St. Francis Xavier College (Colégio São Francisco Xavier) is a Brazilian co-educational Catholic school located in the Subprefecture of Ipiranga of the city of São Paulo. It was founded by the Jesuits in 1928 and covers kindergarten through high school.
Guido del Toro arrived in Brazil from Italy in 1914 and dedicated himself to the evangelization of Japanese immigrants. In 1928, he founded Japanese Catholic College of St. Francis Xavier in a rented house on Liberty Street. He received the present property in 1929 and by 1931 resituated the school there, still dedicated to serving the Japanese.
In 1950, it grew to being a primary and gymnasium. With the completion of a new building in 1966, it became a high school and took the name St. Francis Xavier College.