| Event: | Squash |
| Games: | 2018 Central American and Caribbean Games |
| Venue: | Club Campestre de Cali |
| Location: |  Cali |
| Dates: | 20–26 July |
| Prev: | 2014 |
| Next: | 2026 |
The squash competition at the 2018 Central American and Caribbean Games was held from 20 to 26 July at the Club Campestre de Cali in Cali, Colombia.
| Singles[1] | ||||
| Doubles[2] | Arturo Salazar César Salazar | Andrés Herrera Juan Camilo Vargas | Noah Browne Micah Franklin Edwin Enríquez Junior Enríquez | |
| Team[3] | Alfredo Ávila Arturo Salazar César Salazar | Andrés Herrera Miguel Rodríguez Juan Camilo Vargas | Edwin Enríquez Junior Enríquez José Toscano Christopher Binnie Bruce Burrowes Lewis Walters |
| Singles[4] | ||||
| Doubles[5] | Laura Tovar María Tovar | Diana García Samantha Terán | Eilidh Bridgeman Jade Pitcairn Taylor Fernandes Ashley Khalil | |
| Team[6] | Dina Anguiano Diana García Samantha Terán | Catalina Peláez Laura Tovar María Tovar | Meagan Best Amanda Haywood Jada Smith-Padmore Eilidh Bridgeman Jade Pitcairn Marlene West |
| Doubles[7] | Alfredo Ávila Diana García | Catalina Peláez Miguel Rodríguez | Cameron Stafford Marlene West Winifer Bonilla José Toscano |