SpoIVB peptidase explained

SpoIVB peptidase
Ec Number:3.4.21.116
Cas Number:296241-18-4

SpoIVB peptidase (sporulation factor IV B protease) is an enzyme.[1] [2] [3] [4] This enzyme catalyses the following chemical reaction

Self-cleaves Val52-Asn53, Ala62-Phe63 and Val74-Thr75 at the N-terminus of SpoIVB

This enzyme participates in gene expression during the later stages of spore formation in Bacillus subtilis.

Notes and References

  1. Wakeley PR, Dorazi R, Hoa NT, Bowyer JR, Cutting SM . Proteolysis of SpolVB is a critical determinant in signalling of Pro-sigmaK processing in Bacillus subtilis . Molecular Microbiology . 36 . 6 . 1336–48 . June 2000 . 10931284 . 10.1046/j.1365-2958.2000.01946.x . free .
  2. Hoa NT, Brannigan JA, Cutting SM . The PDZ domain of the SpoIVB serine peptidase facilitates multiple functions . Journal of Bacteriology . 183 . 14 . 4364–73 . July 2001 . 11418578 . 95327 . 10.1128/jb.183.14.4364-4373.2001 .
  3. Hoa NT, Brannigan JA, Cutting SM . The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases . Journal of Bacteriology . 184 . 1 . 191–9 . January 2002 . 11741860 . 134772 . 10.1128/jb.184.1.191-199.2002 .
  4. Dong TC, Cutting SM . SpoIVB-mediated cleavage of SpoIVFA could provide the intercellular signal to activate processing of Pro-sigmaK in Bacillus subtilis . Molecular Microbiology . 49 . 5 . 1425–34 . September 2003 . 12940997 . 10.1046/j.1365-2958.2003.03651.x . free .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "SpoIVB peptidase".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.