| Spilaio | |
| Name Local: | Σπήλαιο |
| Type: | community |
| Coordinates: | 41.65°N 45°W |
| Periph: | East Macedonia and Thrace |
| Periphunit: | Evros |
| Municipality: | Orestiada |
| Municunit: | Trigono |
| Population As Of: | 2021 |
| Population: | 230 |
Spilaio (Greek: Σπήλαιο meaning cave) is a village in the northern part of the Evros regional unit in Greece. It is in the municipal unit of Trigono. It is in a relatively flat, agricultural area. The nearest larger villages are Dikaia to its north, and Plati to its southeast.
| Year | Population | |
|---|---|---|
| 1981 | 603 | |
| 1991 | 590 | |
| 2001 | 443 | |
| 2011 | 334 | |
| 2021 | 230 |
The village was founded by the Ottoman Turks, it was known as İspitli then. After a brief period of Bulgarian rule between 1913 and 1919, it became part of Greece. As a result its Bulgarian and Turkish population was exchanged with Greek refugees, mainly from today's Turkey.