Sphinx (gene) explained

In molecular biology, Sphinx (spx) is a long non-coding RNA found in Drosophila. It is expressed in the brain, within the antennal lobe and inner antennocerebral tract.[1] It is involved in the regulation of male courtship behaviour, this may be via olfactory neuron mediated regulation. Sphinx may act as a negative regulator of target genes.[2] It is a chimeric gene, originating from a retroposed sequence of the ATP synthase chain F gene from chromosome 2 to chromosome 4. Nearby sequences were recruited to form an intron and an exon of this chimeric gene.[3]

See also

Notes and References

  1. Chen . Y. . Dai . H. . Chen . S. . Zhang . L. . Long . M. . Kango-Singh . Madhuri . Highly Tissue Specific Expression of Sphinx Supports Its Male Courtship Related Role in Drosophila melanogaster . 10.1371/journal.pone.0018853 . PLOS ONE . 6 . 4 . e18853 . 3082539 . 2011 . 21541324. free .
  2. Dai . H. . Chen . Y. . Chen . S. . Mao . Q. . Kennedy . D. . Landback . P. . Eyre-Walker . A. . Du . W. . Long . M. . The evolution of courtship behaviors through the origination of a new gene in Drosophila . 10.1073/pnas.0800693105 . Proceedings of the National Academy of Sciences . 105 . 21 . 7478–7483 . 2396706 . 2008 . 18508971. free .
  3. Wang . W. . Brunet . F. G. . Nevo . E. . Long . M. . Origin of sphinx, a young chimeric RNA gene in Drosophilamelanogaster . 10.1073/pnas.072066399 . Proceedings of the National Academy of Sciences . 99 . 7 . 4448–4453 . 123668 . 2002 . 11904380. free .

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