Sphingosine beta-galactosyltransferase explained

sphingosine beta-galactosyltransferase
Ec Number:2.4.1.23
Cas Number:9032-90-0
Go Code:0047258

In enzymology, a sphingosine beta-galactosyltransferase is an enzyme that catalyzes the chemical reaction[1]

UDP-galactose + sphingosine

\rightleftharpoons

UDP + psychosine

Thus, the two substrates of this enzyme are UDP-galactose and sphingosine, whereas its two products are UDP and psychosine.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:sphingosine 1-beta-galactosyltransferase. Other names in common use include psychosine-UDP galactosyltransferase, galactosyl-sphingosine transferase, psychosine-uridine diphosphate galactosyltransferase, UDP-galactose:sphingosine O-galactosyl transferase, uridine diphosphogalactose-sphingosine beta-galactosyltransferase, and UDP-galactose:sphingosine 1-beta-galactotransferase. This enzyme participates in sphingolipid metabolism.

Notes and References

  1. Cleland WW, Kennedy EP . The enzymatic synthesis of psychosine . The Journal of Biological Chemistry . 235 . 45–51 . January 1960 . 13810623 .