| Sphephelo Mayaba | |
| Birth Date: | 31 May 1987 |
| Birth Place: | Pietermaritzburg, South Africa |
| School: | Pinetown Boys' High School |
| University: | UNISA |
| Position: | Prop |
| Currentclub: | College Rovers |
| Youthyears1: | 2007 |
| Years1: | 2009 |
| Apps1: | 2 |
| Points1: | 0 |
| Years2: | 2010 |
| Apps2: | 2 |
| Points2: | 0 |
| Amatyears1: | 2015–present |
| Amatteam1: | College Rovers |
| Clubupdate: | 4 February 2014 |
Sphephelo Mayaba (born 31 May 1987) is a South African rugby union player, currently playing for KwaZulu-Natal club side College Rovers.
He was born in Pietermaritzburg and was included in the squad for the 2009 Vodacom Cup competition, before moving on to the in 2010.