| Official Name: | Spera |
| Pushpin Map: | Afghanistan |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location in Afghanistan |
| Pushpin Mapsize: | 300 |
| Subdivision Type: | Country |
| Subdivision Name: |  Afghanistan |
| Subdivision Type1: | Province |
| Subdivision Name1: | Khost Province |
| Subdivision Type2: | District |
| Subdivision Name2: | Spera District |
| Unit Pref: | Imperial |
| Population Blank1 Title: | Ethnicities |
| Population Blank2 Title: | Religions |
| Coordinates: | 33.2022°N 69.5161°W |
| Elevation M: | 1790 |
Spera (also spelt Sperah and Speyrah) is a village and the district center of Spera District, Khost Province, Afghanistan. It is located on 33.2022°N 69.5161°W at 1,790 m altitude. The town is located within the heartland of the Zadran tribe of Pashtuns.[1] During the US occupation of Afghanistan, Spera sat along a highly used smuggling route from Pakistan into Afghanistan. The area was known to harbor many ex members of both the Taliban and the Al Qaeda.
Spera is the location where United States Army Ranger Pat Tillman was fatally shot and killed by friendly fire in 2004.[2]