| Spencer Brook | |
| Pushpin Map: | New York |
| Pushpin Map Caption: | Location of the mouth of Spencer Brook |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | New York |
| Subdivision Type4: | County |
| Subdivision Name4: | Delaware |
| Source1 Coordinates: | 42.0767°N -75.16°W |
| Mouth: | Chase Brook |
| Mouth Coordinates: | 42.0934°N -75.1752°W[1] |
| Mouth Elevation: | 1348feet |
Spencer Brook is a river in Delaware County, New York. It flows into Chase Brook east of Rock Rift.