Spence Lake is a community in the Canadian province of Manitoba. It is located south of Meadow Portage and was likely named for a local rancher, John Spence.
In the 2021 Census of Population conducted by Statistics Canada, Spence Lake had a population of 70 living in 39 of its 85 total private dwellings, a change of from its 2016 population of 53. With a land area of, it had a population density of in 2021.[1]