| Image Coa: | DEU Spelle COA.png |
| Coordinates: | 52.3667°N 35°W |
| Image Plan: | Spelle in EL.svg |
| State: | Niedersachsen |
| District: | Emsland |
| Samtgemeinde: | Spelle |
| Elevation: | 35 |
| Area: | 34.2 |
| Postal Code: | 48480 |
| Area Code: | 0 59 77 |
| Licence: | EL |
| Gemeindeschlüssel: | 03 4 54 049 |
| Mayor: | Andreas Wenninghoff |
| Party: | CDU |
Spelle is a municipality in the Emsland district, in Lower Saxony, Germany. It is situated approximately 20 km southeast of Lingen, and 10 km north of Rheine.
Spelle is also the seat of the Samtgemeinde ("collective municipality") Spelle.