Infante was one of a class of three 70-gun ships ordered in 1748 to a specification laid down by Ciprian Autran, and was designed and built at Havana by Pedro de Torres. She was laid down on 3 June 1748 and launched on 20 June 1750. She and her sisters Galicia and Princesa were commissioned together on 15 August 1751, and left Havana (together with the equally new 80-gun Rayo) on 1 March 1752 as a squadron under the overall command of Jefe de escuadra Francisco Ponce de Leon, arriving at Cadiz on 30 April.[1]
She was captured by the Royal Navy on 13 August 1762, and commissioned as the third rate HMS Infanta (note change in spelling). She was sold out of the navy in 1775.