SOX15 explained

Protein SOX-15 is a protein that in humans is encoded by the SOX15 gene.^{[1] [2] [3]}

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.^[4]

See also

• SOX genes

Further reading

• Wilson M, Koopman P . Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators. . Curr. Opin. Genet. Dev. . 12 . 4 . 441–6 . 2003 . 12100890 . 10.1016/S0959-437X(02)00323-4 .
• Schepers GE, Teasdale RD, Koopman P . Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families. . Dev. Cell . 3 . 2 . 167–70 . 2002 . 12194848 . 10.1016/S1534-5807(02)00223-X . free .
• Gozé C, Poulat F, Berta P . Partial cloning of SOX-11 and SOX-12, two new human SOX genes. . Nucleic Acids Res. . 21 . 12 . 2943 . 1993 . 8332506 . 10.1093/nar/21.12.2943 . 309692 .
• Hiraoka Y, Ogawa M, Sakai Y, etal . Isolation and expression of a human SRY-related cDNA hSOX20. . Biochim. Biophys. Acta . 1396 . 2 . 132–7 . 1998 . 9540826 . 10.1016/s0167-4781(97)00186-3. free .
• Cremazy F, Soullier S, Berta P, Jay P . Further complexity of the human SOX gene family revealed by the combined use of highly degenerate primers and nested PCR. . FEBS Lett. . 438 . 3 . 311–4 . 1998 . 9827568 . 10.1016/S0014-5793(98)01294-0 . 551497 . free .
• Vujić M, Rajić T, Goodfellow PN, Stevanović M . cDNA characterization and high resolution mapping of the human SOX20 gene. . Mamm. Genome . 9 . 12 . 1059–61 . 1999 . 9880678 . 10.1007/s003359900925 . 792477 .
• Miyashita A, Shimizu N, Endo N, etal . Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are clustered in a 40 kb region of mouse chromosome 11. . Gene . 237 . 1 . 53–60 . 1999 . 10524236 . 10.1016/S0378-1119(99)00301-7 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .

Notes and References

1. Meyer J, Wirth J, Held M, Schempp W, Scherer G . SOX20, a new member of the SOX gene family, is located on chromosome 17p13 . Cytogenet Cell Genet . 72 . 2–3 . 246–9 . Jan 1997 . 8978787 . 10.1159/000134200 .
2. Critcher R, Stitson RN, Wade-Martins R, Easty DJ, Farr CJ . Assignment of Sox4 to mouse chromosome 13 bands A3-A5 by fluorescence in situ hybridization; refinement of the human SOX4 location to 6p22.3 and of SOX20 to chromosome 17p12.3 . Cytogenet Cell Genet . 81 . 3–4 . 294–5 . Oct 1998 . 9730625 . 10.1159/000015052 . 2024-07-25 . 46849443 .
3. Web site: Entrez Gene: SOX15 SRY (sex determining region Y)-box 15.
4. Web site: Entrez Gene: SOX15 SRY (sex determining region Y)-box 15.