The Southern Nevada 2A Region is a part of the Nevada Interscholastic Activities Association, governing the mostly-southern part of Nevada for high school athletics. There are currently 10 member schools in the Southern 2A league for the 2011–2012 school year, one of which is located in California (Needles High School).
| School | Nickname | Colors | Address | |||
|---|---|---|---|---|---|---|
| Andre Agassi Prep | Stars | Navy & Burgundy | 1201 West Lake Mead Blvd. Las Vegas, NV 89106 | |||
| Lions | Royal Blue, Gold, & White | 7065 W. Oquendo Las Vegas, NV 89113 | ||||
| Eagles | Navy, White, & Gold | 540 E. Lake Mead Pkwy. Henderson, NV 89015 | ||||
| Cougars | Royal Blue & Silver | 1900 Cougar Dr. Laughlin, NV 89028 | ||||
| Lynx | Red & White | 1111 Edwards St. Panaca, NV 89042 | ||||
| Mustangs | Blue & Silver | 8601 Scholar Ln. Las Vegas, NV 89128 | ||||
| Saints | Red, Black, & Silver | 3900 E. Bonanza Rd. Las Vegas, NV 89110 | ||||
| Needles | Mustangs | Royal Blue & White | 1900 Erin Dr. Needles, CA 92363 | |||
| Wolverines | Burgundy, Black, & White | 2055 Elko Ave. West Wendover, NV 89883 | ||||
| Bobcats | Blue, & White | 1800 Bobcat Dr. Ely, NV 89301 | ||||