| Southern Isabela Medical Center | |
| Coordinates: | 16.6801°N 121.5466°W |
| Location: | Santiago, Isabela |
| Region: | Cagayan Valley |
| Country: | Philippines |
| Funding: | Government |
| Type: | tertiary level hospital |
| Beds: | 350 |
The Southern Isabela Medical Center (SIMC) is a tertiary level government hospital in the Philippines with an authorized bed capacity of three hundred fifty (350).[1] It is located along Zamora Street, Santiago, Isabela.