South Korean humidifier disinfectant case explained

Hangul:가습기 살균제 사건
Hanja:加濕器 殺菌劑 事件
Rr:Gaseupgi salgyunje sageon
Mr:Kasŭpki salgyunje sagŏn

The humidifier disinfectant case was an outbreak of lung diseases in South Korea caused by chemicals contained in humidifier disinfectants.

The outbreak was detected in children between 2006 and 2011, and in adults in the spring of 2011; the mortality rate in children was 58 percent, while among adults, 53 percent died or required lung transplants.[1] Autopsies and epidemiological work, followed up by animal studies, led the South Korean CDC to identify polyhexamethylene guanidine (PHMG) used in humidifier disinfectants as the cause.[1] [2]

The main cause of the lung diseases was the chemicals PHMG, methylchloroisothiazolinone (CMIT), methylisothiazolinone (MIT) and oligo(2-(2-ethoxy)-ethoxyethyl)guanidinium-chloride (PGH).[3] Experiment of South Korean government found pulmonary toxicity of PHMG and PGH[4] [5] PHMG and PGH caused pulmonary fibrosis when experimented on animals. On November 11, 2011, six humidifier disinfectants which contain PHMG and PGH were recovered. PHMG and PGH was banned in 2011, and new cases ceased occurring.[1] [2]

However, later on, the Korea Centers for Disease Control and Prevention did not find a causal relationship that CMIT and MIT in humidifier disinfectants cause pulmonary fibrosis. This result, still, did not mean that CMIT and MIT were safe,[4] as the chemicals also affected the brain and skin to varying extents.[6] At least five victims used CMIT or MIT-based humidifier disinfectants.[7] [8]

Most victims used Reckitt Benckiser's humidifier disinfectant, Oxy Ssak Ssak (Korean: 옥시싹싹), which led the British firm to various court indictments in the years following 2011.[9] [10] [11]

The South Korean film Air Murder is based on these events.

See also

Notes and References

  1. 26024345. 4610354. 2015. Cummings. K. J.. Occupational and environmental bronchiolar disorders. Seminars in Respiratory and Critical Care Medicine. 36. 3. 366–78. Kreiss. K.. 10.1055/s-0035-1549452.
  2. Book: Dirk W. Lachenmeier . Side Effects of Drugs Annual . Chapter 24 – Antiseptic Drugs and Disinfectants . 37 . 2015 . 273–279 . 10.1016/bs.seda.2015.06.005. 9780444635259 .
  3. Web site: '가습기살균제' 새 재판부 "사회적 참사라는 성찰 아래 공방해야". November 12, 2019. The Dong-a Ilbo.
  4. Web site: 알림 > 보도설명 내용보기 " [4월12일, 경향신문] 보건복지부는 ´독성 없다던 가습기살균제, 환경부선 작년 ´유독물´ 지정´, ´환경부 "가습기 살균 물질 극소량 노출된 흰쥐 절반이 죽어" 관련 보도 해명자료 " | 힘이 되는 평생 친구, 보건복지부]. www.mohw.go.kr.
  5. Web site: 가습기살균제, 폐손상 최종 확인. ktv.go.kr.
  6. Korean Journal of Environmental Biology ::

    . www.ebr.or.kr. 10.11626/KJEB.2020.38.2.271 . 225755701 .
  7. Web site: 가습기살균제 위해 성분 2종 유독물 지정. KBS 뉴스.
  8. Web site: 정부 '괜찮다'던 가습기살균제에 18명 사망, 40명 환자 - 고발뉴스닷컴. www.gobalnews.com.
  9. Web site: '가습기 살균제' 최대 피해낸 '옥시싹싹' 독성실험없이 출시. April 27, 2016. Yonhap News Agency.
  10. Web site: 가습기 살균제 무죄, 2심은 뒤집힐까. 이 . 효상. December 26, 2022. weekly.khan.co.kr.
  11. Web site: 가습기살균제 참사 항소심 '게임 체인저 '부상, 왜?. December 27, 2022. www.ilyosisa.co.kr.