| State: | SC |
| Type: | SC |
| Route: | 358 |
| Alternate Name: | Holly Springs Road |
| Map Custom: | yes |
| Length Mi: | 3.330 |
| Length Ref: | [1] |
| Direction A: | West |
| Terminus A: | near Lyman |
| Direction B: | East |
| Terminus B: | in Lyman |
| Counties: | Spartanburg |
| Previous Type: | SC |
| Previous Route: | 357 |
| Next Type: | SC |
| Next Route: | 362 |
South Carolina Highway 358 (SC 358) is a 3.33miles state highway in the western part of the U.S. state of South Carolina. It travels from Lyman through more rural and suburban parts of Spartanburg County.
The highway starts at SC 357 northwest of Lyman. It heads along the two-lane Holly Springs Road towards central Lyman passing numerous houses, some churches, and a pair of schools. As it approaches its terminus within the town limits of Lyman, it enters a small commercial district. SC 358 ends at an intersection with SC 129 and SC 292, about 300feet northeast of SC 129's terminus at U.S. Route 29.