| State: | SC |
| Type: | SC |
| Route: | 219 |
| Map: | SC 219 map.svg |
| Length Mi: | 9.030 |
| Length Ref: | [1] |
| Established: | 1937 |
| Direction A: | West |
| Terminus A: | in Newberry |
| Junction: | near Newberry |
| Direction B: | East |
| Terminus B: | north of Pomaria |
| Counties: | Newberry |
| Previous Type: | SC |
| Previous Route: | 217 |
| Next Type: | US |
| Next Route: | 221 |
South Carolina Highway 219 (SC 219) is a 9.03adj=midNaNadj=mid highway in the U.S. state of South Carolina. The highway is designated on an east–west direction, from SC 34 in Newberry to U.S. Route 176 (US 176).