| State: | SC |
| Type: | SC |
| Route: | 164 |
| Map: | SC 164 map.svg |
| Length Mi: | 2.500 |
| Length Ref: | [1] |
| Direction A: | West |
| Terminus A: | near Hollywood |
| Direction B: | East |
| Terminus B: | in Hollywood |
| Counties: | Charleston |
| Previous Type: | SC |
| Previous Route: | 162 |
| Next Type: | SC |
| Next Route: | 165 |
South Carolina Highway 164 (SC 164) is a 2.5adj=midNaNadj=mid state highway in the U.S. state of South Carolina. Most of the highway travels through Hollywood and acts as a shortcut between Hollywood and Edisto Beach.
SC 164 begins at an intersection with SC 174 west-southwest of Hollywood, within Charleston County, where the roadway continues as Willtown Road. It travels to the northeast as a two-lane road with a 55mph speed limit. It enters the city limits of Hollywood. After a short distance, SC 164 meets its eastern terminus, an intersection with SC 162.