| State: | SC |
| Type: | SC |
| Route: | 153 |
| Map: | SC 153 map.svg |
| Length Mi: | 11.510 |
| Length Ref: | [1] [2] [3] |
| Established: | 1960s |
| Direction A: | South |
| Terminus A: | Brown Road near Powdersville |
| Junction: |
|
| Direction B: | North |
| Terminus B: | Saluda Dam Road near Easley |
| Counties: | Greenville, Anderson, Pickens |
| Previous Type: | SC |
| Previous Route: | 151 |
| Next Type: | SC |
| Next Route: | 154 |
South Carolina Highway 153 (SC 153) is a 11.51miles state highway, providing a major connection between U.S. Route 123 (US 123) and Interstate 85 (I-85), and also serving as a primary commercial corridor for the suburban Greenville community of Powdersville.
The route travels generally in a southeast to northwest direction, starting unsigned on Brown Road in western Greenville County. The highway almost immediately comes to an interchange with Southern Connector Toll Road (I-185). The two-lane road crosses over the Saluda River into Anderson County where it then meets I-85 at exit 40. From I-85 to US 123 in Pickens County, SC 153 is a four-lane road that is relatively developed with commercial land uses. Continuing north as a two-lane with turn median and flanked with a multi-use path, SC 153 ends at Saluda Dam Road.
On December 8, 2020, SC 153 was extended 4.4miles north from US 123 to Saluda Dam Road (S-39-36).[4]