| State: | SC |
| Type: | SC |
| Route: | 114 |
| Map: | SC 114 map.svg |
| Length Mi: | 6.360 |
| Length Ref: | [1] |
| Direction A: | West |
| Terminus A: | north of Bonham |
| Junction: | near Jonesville |
| Direction B: | East |
| Terminus B: | northeast of Jonesville |
| Counties: | Union |
| Previous Type: | SC |
| Previous Route: | 113 |
| Next Type: | SC |
| Next Route: | 116 |
South Carolina Highway 114 (SC 114) is a 6.36adj=midNaNadj=mid state highway in the U.S. state of South Carolina. The highway travels through rural areas of Union County. The highway has both termini at SC 18 and passes to the east of Jonesville. It is officially designated as a west–east highway, but is physically north–south.
SC 114 begins at an intersection with SC 18 (Jonesville Highway) north of Bonham, within Union County. It travels to the north-northeast to an intersection with SC 9 (Jonesville–Lockhart Highway). The highway curves to the northwest, crosses over Sandy Run Creek, and meets its northern terminus, another intersection with SC 18.