| Npc: | RSA |
| Npcname: | South African Sports Confederation and Olympic Committee |
| Games: | Summer Paralympics |
| Year: | 2000 |
| Location: | Sydney |
| Competitors: | 64 (50 male, 14 female) |
| Rank: | 13 |
| Gold: | 13 |
| Silver: | 12 |
| Bronze: | 13 |
| Appearances: | auto |
There were 14 female and 50 male athletes representing the country at the 2000 Summer Paralympics and finished 13th on the medal table.
| Medal | Name | Sport | Event | |
|---|---|---|---|---|
| Men's 100m T13 | ||||
| Men's 200m T13 | ||||
| Men's 800m T38 | ||||
| Men's discus F42 | ||||
| Men's shot put F37 | ||||
| Men's shot put F42 | ||||
| Men's shot put F57 | ||||
| Men's pentathlon P42 | ||||
| Women's discus F37 | ||||
| Women's javelin F37 | ||||
| Women's javelin F52-54 | ||||
| Men's 50m freestyle S12 | ||||
| Men's 100m freestyle S12 | ||||
| Men's 400m T13 | ||||
| Men's marathon T54 | ||||
| Men's javelin F37 | ||||
| Men's javelin F42 | ||||
| Men's long jump F37 | ||||
| Women's discus F51-54 | ||||
| Women's shot put F33-34 | ||||
| Men's 50m freestyle S10 | ||||
| Men's 50m freestyle S13 | ||||
| Men's 100m breaststroke SB5 | ||||
| Men's 100m freestyle S13 | ||||
| Men's 200m individual medley SM6 | ||||
| Men's 400m T38 | ||||
| Men's 400m T54 | ||||
| Men's high jump F20 | ||||
| Men's high jump F46 | ||||
| Women's discus F33-34 | ||||
| Women's discus F37 | ||||
| Women's shot put F37 | ||||
| Mixed bicycle time trial CP div 3 | ||||
| Women's -56 kg | ||||
| Men's 50m freestyle S14 | ||||
| Men's 100m breaststroke SB9 | ||||
| Men's 100m butterfly S13 | ||||
| Men's 200m freestyle S14 |