| South-Central Zone of São Paulo | |
| Native Name: | Zona Centro-Sul |
| Native Name Lang: | pt |
| Subdivision Type: | Country |
| Subdivision Name: |  Brazil |
| Subdivision Type1: | State |
| Subdivision Name1: | São Paulo |
| Subdivision Type2: | City |
| Subdivision Name2: | São Paulo |
| Population: | 731,758 |
| Parts Type: | Subprefectures |
| Parts Style: | list |
| Parts: | South-Central Zone |
| P1: | Santo Amaro |
| P2: | Vila Mariana |
| P3: | Jabaquara |
The South-Central Zone is an Administrative Zone of São Paulo, Brazil.[1] According to the 2010 census, it has a population of 731,758 inhabitants.
It is a region that is in constant development, with housing neighborhoods more valuable than in the city, such as Klabin, Vila Clementino, and Mirandópolis.
Locals refer to this region simply as South Zone.