STNFR explained

Soluble tumor necrosis factor receptors (sTNFR) are the cleaved-off extracellular domains of transmembrane TNF receptors. They are proposed to enter the bloodstream either via shedding by the enzyme TACE or through exocytosis of the full-length receptor in exosome-like vesicles. Elevated levels of sTNFR are seen in inflammatory processes such as infection, malignancy and autoimmune diseases.[1]

Notes and References

  1. Soluble tumor necrosis factor (TNF) receptor-1 induces apoptosis via reverse TNF signaling and autocrine transforming growth factor-β1. 2005. 10.1096/fj.04-2073fje. 4 February 2015. Waetzig. Georg H.. Rosenstiel. Philip. Arlt. Alexander. Till. Andreas. Bräutigam. Karen. Schäfer. Heiner. Rose-John. Stefan. Seegert. Dirk. Schreiber. Stefan. The FASEB Journal. 19. 1. 91–93. free . 15514103. 86190513.

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